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A four-to-one mixture of erucic acid and oleic acid constitutes Lorenzo's oil; an experimental treatment for a rare neurobiology disorder adrenoleukodystrophy. Mit einer Dichte von 0,86 g/cm 3 ist Erucasäure leichter als Wasser, in dem sie unlöslich ist. Die Erucasäure (auch: Erukasäure) ist eine einfach ungesättigte Fettsäure, die sich in größerer Menge in den Samen von Kreuzblütlern (Brassicaceae), einigen alten Rapssorten, Rübsen und Meerkohlarten findet. Nowadays, rapeseed oils with low levels of erucic acid, including rape oil, colza oil and canola oil, are commercially available. For most humans, the main contributor to … [17] Der Nachweis und die Gehaltsbestimmung von Erucasäure wird in der Regel durch Gaschromatographie des Methylesters durchgeführt; ergänzend kann eine Trennung der ungesättigten Isomere mit Silbernitrat-Dünnschichtchromatographie erfolgen.[8]. For more information on this see: Lipid metabolism. 2  If you produce too much uric acid or are unable to eliminate enough of it, you may have elevated serum urate levels, which is known as hyperuricemia. With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter. EFSA Panel on Contaminants in the Food Chain (CONTAM): Diese Seite wurde zuletzt am 7. Erucasäure wird vom Oxidationssystem der Mitochondrien schlechter abgebaut als andere Fettsäuren. This makes it especially useful in the manufacture of emulsions to coat photographic films and papers. Da Erucasäure ernährungstechnisch problematisch ist (pathologische Veränderung des Herzmuskels, Herzverfettung und Verursachung von Wachstumsverzögerungen im Tierversuch), konnte Raps früher nicht zur Herstellung von Speiseöl (Rüböl) verwendet werden. Wie auch andere langkettige Fettsäuren blockiert Erucasäure vermutlich einige der beteiligten Enzyme, sodass auch andere Fettsäuren langsamer abgebaut werden. For industrial purposes, a High-Erucic Acid Rapeseed (HEAR) has been developed. This is known as the n-9 position. For more information on this see: Lipid metabolism. [6] In den alten Rapsöl-Sorten war ihr Anteil höher als in modernen. © 1997-2020 LUMITOS AG, All rights reserved, https://www.chemeurope.com/en/encyclopedia/Erucic_acid.html, Your browser is not current. A recent study recorded the higher rates of lung cancer in countries with populations that cook over solid fuel wood and biomass fires and stoves. Sehr hohe Dosen von Erucasäure führen zu Herzmuskelverfettung. The high percentage of erucic acid in mustard oil has led to its being banned for food use in the European Union and other countries. Canola oil contains less than 5% erucic acid (Burrows and Tyrl, 2013). Erucic acid is the trivial name of the fatty acid cis-13-docosenoic acid and occurs at high concentrations mainly in the seeds of species of the Brassicaceae (e.g. Choline and inositol offer some protection against this damage,[16] while alpha-linolenic acid may aggravate it. Erucic acid is broken down in the human body by enzymes (long-chain acyl-coenzyme A (CoA) dehydrogenase) produced in the liver, which chop it into shorter-chain fatty acids, which are, in turn, broken down. Mit einer Dichte von 0,86 g/cm3 ist Erucasäure leichter als Wasser, in dem sie unlöslich ist. Its ability to polymerize and dry means it can be - and is - used as a binder for oil paints. Erucic acid is a naturally occurring fatty acid found in both OSR and related species (including several weed species associated with arable systems). It is produced naturally (together with other fatty acids) across a great range of green plants, but especially so in members of the brassica family. Ihr Methylester Methylerucat wird als Bezugssubstanz für die Gaschromatographie verwendet. Blood uric acid levels above 7 are considered uncontrolled. Erucasäure ist ein weißer, kristalliner Feststoff der bei 33,5 °C schmilzt und bei 358 °C siedet. [10]. but is not metabolized there.[17]. rape seed or mustard seed). [9], Epidemiological studies suggest that, in regions where mustard oil is still used in a traditional manner, mustard oil may afford some protection against cardiovascular diseases. Allerdings gibt es mittlerweile erucasäurearme Senfsorten mit einem Erucasäureanteil von 1,1 %, die als Lebensmittel unbedenklich sind. Like other fatty acids, it gets converted into surfactants. Care needs to be taken with such epidemiological studies in order to exclude the possibility of early deaths from other causes skewing the results. Studies on rats show lipodosis problems when fed high quantities of erucic acid, however, so this did not hinder saleability. Such varieties have a low erucic acid content, making seeds suitable for both human and animal consumption. [13] The plant breeding industry later changed "low erucic acid" to be its unique selling proposition over that of its competitors. Risk of diabetes and kidney disease. Erucic acid will readily form many organic compounds. Burkhard Fugmann, Susanne Lang-Fugmann, Wolfgang Steglich: https://de.wikipedia.org/w/index.php?title=Erucasäure&oldid=196599154, „Creative Commons Attribution/Share Alike“, löslich in vielen organischen Lösungsmitteln. Its high tolerance to temperature makes it suitable for transmission oil. Your browser does not support JavaScript. Thalidomide poisoning showed the importance and value of good human epidemiological studies over that of animal studies. to the accumulation and retention of cardiac lipid.”[7] Before this process was fully understood, however, there developed a misunderstanding, which continues to be repeated until this day. Because of this, babies should not be given foods high in erucic acid. It is known as monounsaturated because it has only one double-bonded carbon atom in its fatty acid chain. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE. Being a hydrocarbon of high calorific value, with a very low flash point, high cetane rating, and good lubrication qualities, erucic acid can be a valuable component of bio-diesel. We treated 12 newly diagnosed ALD patients with a diet enriched with erucic acid and oleic acid for 2 to 19 months. Adding this ability to its polymerizing characteristics makes it very suitable for use as organic matrices that need to be polymeric. Most UK-grown OSR varieties are ‘double-low’ – also called ‘double-zero’ and ‘00’. The Food Standards Agency is advising against eating all the products identified as having illegal levels of erucic acid in both surveys. Selbst beim häufigen Verzehr von Rapsöl, der aufgrund des hohen Anteils von ungesättigten Fettsäuren vorteilhaft sein kann, und von Rapsölprodukten wird diese Dosis nicht erreicht, wenn der Anteil von Erucasäure an den Fettsäuren kleiner ist als 2 %. No negative health effects have ever been documented in humans, although it is advisable not to give un-weaned babies foods containing erucic acid for the reasons given above. [6] In den alten Rapsöl-Sorten war ihr Anteil höher als in modernen. Mean plasma C26:0 concentration decreased to normal by 4 weeks, and the C26:0 … [18] [14] The studies showed that lipidoses suffered by the piglets proved to be only a transient effect; the liver automatically responded by increasing enzyme levels to cope with the unusual diet, and the lipidoses subsided. However, the National Institutes of Health estimates that 6 million US adults suffer from gout at some point in their lives, many of whom have uncontrolled uric acid levels. Erucic acid is a monounsaturated omega-9 fatty acid, denoted 22:1ω9.It has the chemical formula CH 3 (CH 2) 7 CH=CH(CH 2) 11 COOH. In response to the potential safety concerns associated with high levels of erucic acid in rapeseed, efforts have been made to produce cultivars with a low erucic acid trait. [4][5][6] Chariton et al. Normally, women maintain a stable serum urate level between 1.5 to 6.0 mg/dL, while for men it is between 2.5 to 7.0 mg/dL. [16] including adult rats. Find out how LUMITOS supports you with online marketing. When converted into behenyl alcohol (CH3(CH2)21OH), erucic acid has many further uses such as a pour point depressant, enabling liquids to flow at a lower temperature and silver behenate for use in photography.[1]. It is widely used to produce emollients, especially for skin and healthcare products. This is temporary and reversible. A complex cocktail of many different erucic acid compounds are commonly used in just one roll of color film. See below. Lorenzos Öl, eine Mischung aus Glycerintrioleat und Glycerintrierucat (den Triglyceriden der Ölsäure und der Erucasäure), soll bei Fettstoffwechselstörungen (Adrenoleukodystrophie, Adrenomyeloneuropathie) die Bildung von langkettigen gesättigten Fettsäuren im menschlichen Körper reduzieren. Februar 2020 um 18:07 Uhr bearbeitet. Other potential effects observed in animals – including changes in the weight of the liver, kidney and skeletal muscle – occur at slightly higher doses. Erucic acid has been associated with cardiac injury in cattle and experimental rodents (Burrows and Tyrl, 2013). To use all functions of this page, please activate cookies in your browser. [8] Whether this effect is due to the nature of erucic acid per se to make the blood platelets less sticky, or to the presence of a reasonably high percentage of α-linolenic acid, or to a combination of properties of fresh unrefined oil, is as yet uncertain. Das Molekül, das aus einer Kette von 22 Kohlenstoffatomen besteht, hat genau eine Doppelbindung und ist – wie alle Fettsäuren – eine Carbonsäure. These cultivars can yield 40% to 60% of the total oil recovered as erucic acid. The European Commission requested EFSA to deliver a scientific opinion on the risks for animal and human health related to the presence of erucic acid in feed and food. There are not many studies done on humans with erucic acid; the majority are carried out by the food science industry on animals. Diese dürfen, bezogen auf den Gesamtgehalt an Fettsäuren, nicht mehr als 5 % Erucasäure enthalten. Based on animal studies in adult pigs and piglets, it can be reasonably presumed that, in human infants that have not yet been weaned, these particular enzymes are in short supply (as the mother's milk is the normal food source during this period), although not totally absent. Studies on rats have shown that they are less able to digest vegetable fats (whether or not they contain erucic acid) than humans and pigs. It promotes myocardial lesions in several animal models, While it was possible to breed out much of the pungent-tasting glucosinolates, one of the dominant erucic acid genes would get stripped out of the genome as well, greatly reducing its valuable erucic acid content. In a double-blind crossover study of patients who were on chronic oleic acid (C18:1) therapy, addition of erucic acid to the diet led to a further reduction in plasma hexacosanoic acid (C26:0) concentration. Sie findet sich auch im Brokkolisamenöl und im Senföl und kommt in Seetier- und Fischölen vor.[7]. Mai 1977 (BGBl I 1977, S. 782). Im Senföl, das in Indien bis heute verwendet wird, ist die Säure ebenfalls enthalten; dort scheint der Verzehr nicht mit negativen Auswirkungen auf die Gesundheit verbunden zu sein. In one case, neonate piglets that have a limited ability to absorb these fats had their normal sow's milk replaced solely with rapeseed oil for one hundred percent of their calorific needs. Erucic acid is preferentially absorbed in myocardium tissue[19] In Alkoholen wie Methanol oder Ethanol ist sie löslich. Find out more about the company LUMITOS and our team. Fully refined rapessed oils of high (regular rapeseed oil, B. campestris) and low erucic acid content (Span oil, B. campestris; commercially hydrogenated Span oil and Zephyr oil, B. napus) and soybean oil were fed to male and female Sprague-Dawley rats at a level of 15% by weight in the diet. 782 ) a variety of cooking oils also did this at similar heats,. Treatment for a rare neurobiology disorder adrenoleukodystrophy 00 ’ von Emulgatoren, oberflächenaktiven. ( CONTAM ): diese Seite wurde zuletzt am 7 acid for 2 19... Matrices that need to be taken with such epidemiological studies in order to the... 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Been considerably reduced to make it more palatable to humans and cattle marketing! Blockiert Erucasäure vermutlich einige der beteiligten Enzyme, sodass auch andere langkettige Fettsäuren blockiert Erucasäure vermutlich einige der beteiligten,...

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